Developing Human Pluripotent Stem Cell-Based Cerebral Organoids with a Controllable Microglia Ratio for Modeling Brain Development and Pathology

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Justin.choi
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Investigators reported a new brain region-specific, microglia-containing organoid model by co-culturing human PSC-derived primitive neural progenitor cells and primitive macrophage progenitors.
[Stem Cell Reports]
Xu, R., Boreland, A. J., Li, X., Erickson, C., Jin, M., Atkins, C., Pang, Z. P., Daniels, B. P., & Jiang, P. (2021). Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology. Stem Cell Reports, 0(0). https://doi.org/10.1016/j.stemcr.2021.06.011 Cite
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