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Pulmonary Cell Newspigallocatechin-3-gallate (EGCG) induced an internal Ca2+ increase in prostate cancer (PCa) cells by a multi-step mechanism. Researchers confirmed the possibility of using EGCG as a synergistic adjuvant in combined therapies for recalcitrant malignancies like androgen-independent PCa.
[Life Sciences]
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Marchetti, C., Gavazzo, P., & Burlando, B. (2020). Epigallocatechin-3-gallate mobilizes intracellular Ca2+ in prostate cancer cells through combined Ca2+ entry and Ca2+-induced Ca2+ release. Life Sciences, 258, 118232. https://doi.org/10.1016/j.lfs.2020.118232 Cite
