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Pulmonary Cell NewsResearchers demonstrated that Rac1 is overactive in the airways of patients with severe asthma and is essential for airway smooth muscle cell proliferation.
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Dilasser, F., Rose, L., Hassoun, D., Klein, M., Rousselle, M., Brosseau, C., Guignabert, C., Taillé, C., Dombret, M. C., Candia, L. D., Heddebaut, N., Bouchaud, G., Pretolani, M., Magnan, A., Loirand, G., & Sauzeau, V. (2021). Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling. Thorax. https://doi.org/10.1136/thoraxjnl-2020-216271 Cite
