Researchers ivestigated the immune response in acute or convalescent COVID19 patients. They characterized the peripheral blood mononuclear cells using flow cytometry and found that CD8+ T cells were significantly subsided in moderate COVID-19 and convalescent patients.
[Heliyon]
6445212 7W44BDIM items 1 apa 0 default asc 1 162936 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-60f496526ffb9cbe86a7e9950f04a57f%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%227W44BDIM%22%2C%22library%22%3A%7B%22id%22%3A6445212%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Singh%20et%20al.%22%2C%22parsedDate%22%3A%222021-05-27%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESingh%2C%20Y.%2C%20Trautwein%2C%20C.%2C%20Fendel%2C%20R.%2C%20Krickeberg%2C%20N.%2C%20Berezhnoy%2C%20G.%2C%20Bissinger%2C%20R.%2C%20Ossowski%2C%20S.%2C%20Salker%2C%20M.%20S.%2C%20Casadei%2C%20N.%2C%20Riess%2C%20O.%2C%20Altm%26%23xFC%3Bller%2C%20J.%2C%20Angelov%2C%20A.%2C%20Bals%2C%20R.%2C%20Bartholom%26%23xE4%3Bus%2C%20A.%2C%20Becker%2C%20A.%2C%20Bezdan%2C%20D.%2C%20Bonifacio%2C%20E.%2C%20Bork%2C%20P.%2C%20Casadei%2C%20N.%2C%20%26%23x2026%3B%20Vel%26%23xE1%3Bzquez%2C%20I.%20A.%20D.%20L.%20R.%20%282021%29.%20SARS-CoV-2%20infection%20paralyzes%20cytotoxic%20and%20metabolic%20functions%20of%20the%20immune%20cells.%20%3Ci%3EHeliyon%3C%5C%2Fi%3E%2C%20%3Ci%3E0%3C%5C%2Fi%3E%280%29.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.heliyon.2021.e07147%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.heliyon.2021.e07147%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445212%26amp%3Bitem_key%3D7W44BDIM%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22SARS-CoV-2%20infection%20paralyzes%20cytotoxic%20and%20metabolic%20functions%20of%20the%20immune%20cells%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yogesh%22%2C%22lastName%22%3A%22Singh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Trautwein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rolf%22%2C%22lastName%22%3A%22Fendel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Naomi%22%2C%22lastName%22%3A%22Krickeberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Georgy%22%2C%22lastName%22%3A%22Berezhnoy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rosi%22%2C%22lastName%22%3A%22Bissinger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephan%22%2C%22lastName%22%3A%22Ossowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Madhuri%20S.%22%2C%22lastName%22%3A%22Salker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Casadei%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olaf%22%2C%22lastName%22%3A%22Riess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janine%22%2C%22lastName%22%3A%22Altm%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angel%22%2C%22lastName%22%3A%22Angelov%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Bals%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Bartholom%5Cu00e4us%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anke%22%2C%22lastName%22%3A%22Becker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniela%22%2C%22lastName%22%3A%22Bezdan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ezio%22%2C%22lastName%22%3A%22Bonifacio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peer%22%2C%22lastName%22%3A%22Bork%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Casadei%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Clavel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maria%22%2C%22lastName%22%3A%22Colome-Tatche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Diefenbach%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Dilthey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicole%22%2C%22lastName%22%3A%22Fischer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Konrad%22%2C%22lastName%22%3A%22F%5Cu00f6rstner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00f6ren%22%2C%22lastName%22%3A%22Franzenburg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julia%20Stefanie%22%2C%22lastName%22%3A%22Frick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gisela%22%2C%22lastName%22%3A%22Gabernet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julien%22%2C%22lastName%22%3A%22Gagneur%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tina%22%2C%22lastName%22%3A%22Ganzenm%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Gauder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Goesmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siri%22%2C%22lastName%22%3A%22G%5Cu00f6pel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adam%22%2C%22lastName%22%3A%22Grundhoff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Torsten%22%2C%22lastName%22%3A%22Hain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andr%5Cu00e8%22%2C%22lastName%22%3A%22Heimbach%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Hummel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Iftner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelika%22%2C%22lastName%22%3A%22Iftner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Janssen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00f6rn%22%2C%22lastName%22%3A%22Kalinowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ren%5Cu00e9%22%2C%22lastName%22%3A%22Kallies%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Birte%22%2C%22lastName%22%3A%22Kehr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Kim-Hellmuth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Klein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Kohlbacher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karl%22%2C%22lastName%22%3A%22K%5Cu00f6hrer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Knop%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%20O.%22%2C%22lastName%22%3A%22Korbel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20G.%22%2C%22lastName%22%3A%22Kremsner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Denise%22%2C%22lastName%22%3A%22K%5Cu00fchnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ingo%22%2C%22lastName%22%3A%22Kurth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Landthaler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yang%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliwia%22%2C%22lastName%22%3A%22Makarewicz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manja%22%2C%22lastName%22%3A%22Marz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alice%22%2C%22lastName%22%3A%22McHardy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Mertes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Nahsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22N%5Cu00f6then%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francine%22%2C%22lastName%22%3A%22Ntoumi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22N%5Cu00fcrnberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uwe%22%2C%22lastName%22%3A%22Ohler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephan%22%2C%22lastName%22%3A%22Ossowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00f6rg%22%2C%22lastName%22%3A%22Overmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silke%22%2C%22lastName%22%3A%22Peter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Klaus%22%2C%22lastName%22%3A%22Pfeffer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%20R.%22%2C%22lastName%22%3A%22Poetsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alfred%22%2C%22lastName%22%3A%22P%5Cu00fchler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nikolaus%22%2C%22lastName%22%3A%22Rajewsky%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Ralser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olaf%22%2C%22lastName%22%3A%22Rie%5Cu00df%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephan%22%2C%22lastName%22%3A%22Ripke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulisses%20Nunes%20da%22%2C%22lastName%22%3A%22Rocha%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philip%22%2C%22lastName%22%3A%22Rosenstiel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antoine-Emmanuel%22%2C%22lastName%22%3A%22Saliba%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leif%20Erik%22%2C%22lastName%22%3A%22Sander%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Birgit%22%2C%22lastName%22%3A%22Sawitzki%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philipp%22%2C%22lastName%22%3A%22Schiffer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wulf%22%2C%22lastName%22%3A%22Scheider%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva-Christina%22%2C%22lastName%22%3A%22Schulte%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%20L.%22%2C%22lastName%22%3A%22Schultze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Sczyrba%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yogesh%22%2C%22lastName%22%3A%22Singh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Sonnabend%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Stegle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%22%2C%22lastName%22%3A%22Stoye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Theis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janne%22%2C%22lastName%22%3A%22Vehreschild%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thirumalaisamy%20P.%22%2C%22lastName%22%3A%22Velavan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00f6rg%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Max%20von%22%2C%22lastName%22%3A%22Kleist%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Walker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00f6rn%22%2C%22lastName%22%3A%22Walter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dagmar%22%2C%22lastName%22%3A%22Wieczorek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylke%22%2C%22lastName%22%3A%22Winkler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%22%2C%22lastName%22%3A%22Ziebuhr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simone%22%2C%22lastName%22%3A%22Scheithauer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hajo%22%2C%22lastName%22%3A%22Grundmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%22%2C%22lastName%22%3A%22Schmid-Burgk%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Protzer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Inti%20Alberto%20De%20La%20Rosa%22%2C%22lastName%22%3A%22Vel%5Cu00e1zquez%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021-05-27%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.heliyon.2021.e07147%22%2C%22ISSN%22%3A%222405-8440%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.cell.com%5C%2Fheliyon%5C%2Fabstract%5C%2FS2405-8440%2821%2901250-0%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-06-02T20%3A04%3A52Z%22%7D%7D%5D%7D
Singh, Y., Trautwein, C., Fendel, R., Krickeberg, N., Berezhnoy, G., Bissinger, R., Ossowski, S., Salker, M. S., Casadei, N., Riess, O., Altmüller, J., Angelov, A., Bals, R., Bartholomäus, A., Becker, A., Bezdan, D., Bonifacio, E., Bork, P., Casadei, N., … Velázquez, I. A. D. L. R. (2021). SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells. Heliyon, 0(0). https://doi.org/10.1016/j.heliyon.2021.e07147 Cite