Regulatory T Cells Promote the Stemness of Leukemia Stem Cells through IL10 Cytokine-Related Signaling Pathway

The increased stemness of acute myeloid leukemia (AML) cells promoted by Tregs was verified in vitro and in vivo, and researchers found that blocking the interaction between Tregs and AML cells may be a new approach to target leukemia stem cells in AML treatment.