Oxaliplatin Facilitates Tumor-Infiltration of T Cells and Natural-Killer Cells for Enhanced Tumor Immunotherapy in Lung Cancer Mode

Subcutaneous A549 lung cancer and murine Lewis lung carcinoma (LLC) models were constructed, which were further intravenously injected with platinum-based drugs or concomitant administrated with anti-PD-1 antibody and or anti-NKG2D antibody.