TIM-3 Shuttled by MV3 Cells-Secreted Exosomes Inhibits CD4⁺ T Cell Immune Function and Induces Macrophage M2 Polarization to Promote the Growth and Metastasis of Melanoma Cells

Silencing of TIM-3 shuttled by MV3 cells-derived exosomes improved CD4+ T cell immune function and inhibited macrophage M2 polarization to attenuate the growth and metastasis of melanoma cells.