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Pulmonary Cell NewsInvestigators reported that ApoE was elevated in peripheral blood monocytes in pancreatic ductal adenocarcinoma patients, and plasma ApoE protein levels stratified patient survival.
[Cancer Research]
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Kemp, S. B., Carpenter, E. S., Steele, N. G., Donahue, K. L., Nwosu, Z. C., Pacheco, A., Velez-Delgado, A., Menjivar, R. E., Lima, F., The, S., Espinoza, C. E., Brown, K., Long, D., Lyssiotis, C. A., Rao, A., Zhang, Y., Magliano, M. P. di, & Crawford, H. C. (2021). Apolipoprotein E promotes immune suppression in pancreatic cancer through NF-kB-mediated production of CXCL1. Cancer Research. https://doi.org/10.1158/0008-5472.CAN-20-3929 Cite
