The Isoflavone Puerarin Exerts Anti-Tumor Activity in Pancreatic Ductal Adenocarcinoma by Suppressing mTOR-Mediated Glucose Metabolism

The tumor-suppressive effects of puerarin were determined by both in vitro and in vivo assays. The effects of puerarin on the proliferation, apoptosis, migration and invasion of pancreatic cancer cells, and tumor growth and metastasis in pancreatic ductal adenocarcinoma xenograft mouse model were performed.