The authors showed that cancer stem cells upregulated the immune checkpoint molecule CD276 to evade host immune responses.
[Cell Stem Cell]
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Wang, C., Li, Y., Jia, L., Kim, J. koo, Li, J., Deng, P., Zhang, W., Krebsbach, P. H., & Wang, C.-Y. (2021). CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance. Cell Stem Cell, 0(0). https://doi.org/10.1016/j.stem.2021.04.011 Cite