Scientists designed a meta-analysis to assess gene expression profiles in different breast cancer cell lines focusing on the secretory factors responsible for conversion.
[Cancer Letters]
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Sheta, M., Hassan, G., Afify, S. M., Monzur, S., Kumon, K., Abu Quora, H. A., Farahat, M., Zahra, M. H., Fu, X., Seno, A., & Seno, M. (2021). Chronic exposure to FGF2 converts iPSCs into cancer stem cells with an enhanced integrin/focal adhesion/PI3K/AKT axis. Cancer Letters, 521, 142–154. https://doi.org/10.1016/j.canlet.2021.08.026 Cite