Home Newsletters Immune Regulation News Gain-of-Function p53R172H Mutation Drives Accumulation of Neutrophils in Pancreatic Tumors, Promoting Resistance...

Gain-of-Function p53^R172H Mutation Drives Accumulation of Neutrophils in Pancreatic Tumors, Promoting Resistance to Immunotherapy

Justin.choi

August 24, 2021

Researchers compared the immune profiles generated by Kras^G12D-mutated mouse pancreatic ductal epithelial cells engineered genetically to express the Trp53^R172H mutation with their p53 wild-type control.

[Cell Reports]

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