Alpha-7 Nicotinic Acetylcholine Receptor Agonist Alleviates Psoriasis-Like Inflammation through Inhibition of the STAT3 and NF-κB Signaling Pathway

Researchers analyzed the expression of α7nAchR in human and mouse psoriatic skin tissue. In vivo, PNU-282987 or Methyllycaconitine, a specific agonist or antagonist of α7nAchR, were administered to imiquimod-induced psoriatic mouse models.