Eosinophils Improve Cardiac Function after Myocardial Infarction

By
Justin.choi
-
0
22
Mechanistic studies revealed roles of eosinophil IL4 and cationic protein mEar1 in blocking H2O2– and hypoxia-induced mouse and human cardiomyocyte death, TGF-β-induced cardiac fibroblast Smad2/3 activation, and TNF-α-induced neutrophil adhesion on the heart endothelial cell monolayer.
[Nature Communications]
1254621 {1254621:CV7KKL54} 1 apa 50 default 1 157345 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22CV7KKL54%22%2C%22library%22%3A%7B%22id%22%3A1254621%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Liu%20et%20al.%22%2C%22parsedDate%22%3A%222020-12-16%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLiu%2C%20J.%2C%20Yang%2C%20C.%2C%20Liu%2C%20T.%2C%20Deng%2C%20Z.%2C%20Fang%2C%20W.%2C%20Zhang%2C%20X.%2C%20Li%2C%20J.%2C%20Huang%2C%20Q.%2C%20Liu%2C%20C.%2C%20Wang%2C%20Y.%2C%20Yang%2C%20D.%2C%20Sukhova%2C%20G.%20K.%2C%20Lindholt%2C%20J.%20S.%2C%20Diederichsen%2C%20A.%2C%20Rasmussen%2C%20L.%20M.%2C%20Li%2C%20D.%2C%20Newton%2C%20G.%2C%20Luscinskas%2C%20F.%20W.%2C%20Liu%2C%20L.%2C%20%26%23x2026%3B%20Shi%2C%20G.-P.%20%282020%29.%20Eosinophils%20improve%20cardiac%20function%20after%20myocardial%20infarction.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B11%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%206396.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-020-19297-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-020-19297-5%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D1254621%26amp%3Bitem_key%3DCV7KKL54%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Eosinophils%20improve%20cardiac%20function%20after%20myocardial%20infarction%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jing%22%2C%22lastName%22%3A%22Liu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chongzhe%22%2C%22lastName%22%3A%22Yang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tianxiao%22%2C%22lastName%22%3A%22Liu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Zhiyong%22%2C%22lastName%22%3A%22Deng%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wenqian%22%2C%22lastName%22%3A%22Fang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xian%22%2C%22lastName%22%3A%22Zhang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jie%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qin%22%2C%22lastName%22%3A%22Huang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Conglin%22%2C%22lastName%22%3A%22Liu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yunzhe%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dafeng%22%2C%22lastName%22%3A%22Yang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Galina%20K.%22%2C%22lastName%22%3A%22Sukhova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jes%20S.%22%2C%22lastName%22%3A%22Lindholt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Axel%22%2C%22lastName%22%3A%22Diederichsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lars%20M.%22%2C%22lastName%22%3A%22Rasmussen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dazhu%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gail%22%2C%22lastName%22%3A%22Newton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francis%20W.%22%2C%22lastName%22%3A%22Luscinskas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lijun%22%2C%22lastName%22%3A%22Liu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Libby%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jing%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Junli%22%2C%22lastName%22%3A%22Guo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Guo-Ping%22%2C%22lastName%22%3A%22Shi%22%7D%5D%2C%22abstractNote%22%3A%22%5Cu436c%5Cu696e%5Cu6963%5Cu616c%5Cu2073%5Cu7475%5Cu6469%5Cu6573%5Cu2072%5Cu6576%5Cu6561%5Cu6c20%5Cu6368%5Cu616e%5Cu6765%5Cu7320%5Cu696e%5Cu2062%5Cu6c6f%5Cu6f64%5Cu2065%5Cu6f73%5Cu696e%5Cu6f70%5Cu6869%5Cu6c20%5Cu636f%5Cu756e%5Cu7473%5Cu2061%5Cu6e64%5Cu2065%5Cu6f73%5Cu696e%5Cu6f70%5Cu6869%5Cu6c20%5Cu6361%5Cu7469%5Cu6f6e%5Cu6963%5Cu2070%5Cu726f%5Cu7465%5Cu696e%5Cu7320%5Cu7468%5Cu6174%5Cu206d%5Cu6179%5Cu2073%5Cu6572%5Cu7665%5Cu2061%5Cu7320%5Cu7269%5Cu736b%5Cu2066%5Cu6163%5Cu746f%5Cu7273%5Cu2066%5Cu6f72%5Cu2068%5Cu756d%5Cu616e%5Cu2063%5Cu6f72%5Cu6f6e%5Cu6172%5Cu7920%5Cu6865%5Cu6172%5Cu7420%5Cu6469%5Cu7365%5Cu6173%5Cu6573%5Cu2e20%5Cu4865%5Cu7265%5Cu2077%5Cu6520%5Cu7265%5Cu706f%5Cu7274%5Cu2061%5Cu6e20%5Cu696e%5Cu6372%5Cu6561%5Cu7365%5Cu206f%5Cu6620%5Cu626c%5Cu6f6f%5Cu6420%5Cu6f72%5Cu2068%5Cu6561%5Cu7274%5Cu2065%5Cu6f73%5Cu696e%5Cu6f70%5Cu6869%5Cu6c20%5Cu636f%5Cu756e%5Cu7473%5Cu2069%5Cu6e20%5Cu6875%5Cu6d61%5Cu6e73%5Cu2061%5Cu6e64%5Cu206d%5Cu6963%5Cu6520%5Cu6166%5Cu7465%5Cu7220%5Cu6d79%5Cu6f63%5Cu6172%5Cu6469%5Cu616c%5Cu2069%5Cu6e66%5Cu6172%5Cu6374%5Cu696f%5Cu6e20%5Cu284d%5Cu4929%5Cu2c20%5Cu6d6f%5Cu7374%5Cu6c79%5Cu2069%5Cu6e20%5Cu7468%5Cu6520%5Cu696e%5Cu6661%5Cu7263%5Cu7420%5Cu7265%5Cu6769%5Cu6f6e%5Cu2e20%5Cu4765%5Cu6e65%5Cu7469%5Cu6320%5Cu6f72%5Cu2069%5Cu6e64%5Cu7563%5Cu6962%5Cu6c65%5Cu2064%5Cu6570%5Cu6c65%5Cu7469%5Cu6f6e%5Cu206f%5Cu6620%5Cu656f%5Cu7369%5Cu6e6f%5Cu7068%5Cu696c%5Cu7320%5Cu6578%5Cu6163%5Cu6572%5Cu6261%5Cu7465%5Cu7320%5Cu6361%5Cu7264%5Cu6961%5Cu6320%5Cu6479%5Cu7366%5Cu756e%5Cu6374%5Cu696f%5Cu6e2c%5Cu2063%5Cu656c%5Cu6c20%5Cu6465%5Cu6174%5Cu682c%5Cu2061%5Cu6e64%5Cu2066%5Cu6962%5Cu726f%5Cu7369%5Cu7320%5Cu706f%5Cu7374%5Cu2d4d%5Cu492c%5Cu2077%5Cu6974%5Cu6820%5Cu636f%5Cu6e63%5Cu7572%5Cu7265%5Cu6e74%5Cu2061%5Cu6375%5Cu7465%5Cu2069%5Cu6e63%5Cu7265%5Cu6173%5Cu6520%5Cu6f66%5Cu2068%5Cu6561%5Cu7274%5Cu2061%5Cu6e64%5Cu2063%5Cu6872%5Cu6f6e%5Cu6963%5Cu2069%5Cu6e63%5Cu7265%5Cu6173%5Cu6520%5Cu6f66%5Cu2073%5Cu706c%5Cu656e%5Cu6963%5Cu206e%5Cu6575%5Cu7472%5Cu6f70%5Cu6869%5Cu6c73%5Cu2061%5Cu6e64%5Cu206d%5Cu6f6e%5Cu6f63%5Cu7974%5Cu6573%5Cu2e20%5Cu4d65%5Cu6368%5Cu616e%5Cu6973%5Cu7469%5Cu6320%5Cu7374%5Cu7564%5Cu6965%5Cu7320%5Cu7265%5Cu7665%5Cu616c%5Cu2072%5Cu6f6c%5Cu6573%5Cu206f%5Cu6620%5Cu656f%5Cu7369%5Cu6e6f%5Cu7068%5Cu696c%5Cu2049%5Cu4c34%5Cu2061%5Cu6e64%5Cu2063%5Cu6174%5Cu696f%5Cu6e69%5Cu6320%5Cu7072%5Cu6f74%5Cu6569%5Cu6e20%5Cu6d45%5Cu6172%5Cu3120%5Cu696e%5Cu2062%5Cu6c6f%5Cu636b%5Cu696e%5Cu6720%5Cu4832%5Cu4f32%5Cu2d20%5Cu616e%5Cu6420%5Cu6879%5Cu706f%5Cu7869%5Cu612d%5Cu696e%5Cu6475%5Cu6365%5Cu6420%5Cu6d6f%5Cu7573%5Cu6520%5Cu616e%5Cu6420%5Cu6875%5Cu6d61%5Cu6e20%5Cu6361%5Cu7264%5Cu696f%5Cu6d79%5Cu6f63%5Cu7974%5Cu6520%5Cu6465%5Cu6174%5Cu682c%5Cu2054%5Cu4746%5Cu2dce%5Cub22d%5Cu696e%5Cu6475%5Cu6365%5Cu6420%5Cu6361%5Cu7264%5Cu6961%5Cu6320%5Cu6669%5Cu6272%5Cu6f62%5Cu6c61%5Cu7374%5Cu2053%5Cu6d61%5Cu6432%5Cu2f33%5Cu2061%5Cu6374%5Cu6976%5Cu6174%5Cu696f%5Cu6e2c%5Cu2061%5Cu6e64%5Cu2054%5Cu4e46%5Cu2dce%5Cub12d%5Cu696e%5Cu6475%5Cu6365%5Cu6420%5Cu6e65%5Cu7574%5Cu726f%5Cu7068%5Cu696c%5Cu2061%5Cu6468%5Cu6573%5Cu696f%5Cu6e20%5Cu6f6e%5Cu2074%5Cu6865%5Cu2068%5Cu6561%5Cu7274%5Cu2065%5Cu6e64%5Cu6f74%5Cu6865%5Cu6c69%5Cu616c%5Cu2063%5Cu656c%5Cu6c20%5Cu6d6f%5Cu6e6f%5Cu6c61%5Cu7965%5Cu722e%5Cu2049%5Cu6e20%5Cu7669%5Cu7472%5Cu6f2d%5Cu6375%5Cu6c74%5Cu7572%5Cu6564%5Cu2065%5Cu6f73%5Cu696e%5Cu6f70%5Cu6869%5Cu6c73%5Cu2066%5Cu726f%5Cu6d20%5Cu5754%5Cu206d%5Cu6963%5Cu6520%5Cu6f72%5Cu2072%5Cu6563%5Cu6f6d%5Cu6269%5Cu6e61%5Cu6e74%5Cu206d%5Cu4561%5Cu7231%5Cu2070%5Cu726f%5Cu7465%5Cu696e%5Cu2c20%5Cu6275%5Cu7420%5Cu6e6f%5Cu7420%5Cu656f%5Cu7369%5Cu6e6f%5Cu7068%5Cu696c%5Cu7320%5Cu6672%5Cu6f6d%5Cu2049%5Cu4c34%5Cu2d64%5Cu6566%5Cu6963%5Cu6965%5Cu6e74%5Cu206d%5Cu6963%5Cu652c%5Cu2065%5Cu6666%5Cu6563%5Cu7469%5Cu7665%5Cu6c79%5Cu2063%5Cu6f72%5Cu7265%5Cu6374%5Cu2065%5Cu7861%5Cu6365%5Cu7262%5Cu6174%5Cu6564%5Cu2063%5Cu6172%5Cu6469%5Cu6163%5Cu2064%5Cu7973%5Cu6675%5Cu6e63%5Cu7469%5Cu6f6e%5Cu7320%5Cu696e%5Cu2065%5Cu6f73%5Cu696e%5Cu6f70%5Cu6869%5Cu6c2d%5Cu6465%5Cu6669%5Cu6369%5Cu656e%5Cu7420%5Cue288%5Cu8664%5Cu626c%5Cu4741%5Cu5441%5Cu206d%5Cu6963%5Cu652e%5Cu2054%5Cu6869%5Cu7320%5Cu7374%5Cu7564%5Cu7920%5Cu6573%5Cu7461%5Cu626c%5Cu6973%5Cu6865%5Cu7320%5Cu6120%5Cu6361%5Cu7264%5Cu696f%5Cu7072%5Cu6f74%5Cu6563%5Cu7469%5Cu7665%5Cu2072%5Cu6f6c%5Cu6520%5Cu6f66%5Cu2065%5Cu6f73%5Cu696e%5Cu6f70%5Cu6869%5Cu6c73%5Cu2069%5Cu6e20%5Cu706f%5Cu7374%5Cu2d4d%5Cu4920%5Cu6865%5Cu6172%5Cu7473%3F%22%2C%22date%22%3A%222020-12-16%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-020-19297-5%22%2C%22ISSN%22%3A%222041-1723%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41467-020-19297-5%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222020-12-16T20%3A56%3A57Z%22%7D%7D%5D%7D
Liu, J., Yang, C., Liu, T., Deng, Z., Fang, W., Zhang, X., Li, J., Huang, Q., Liu, C., Wang, Y., Yang, D., Sukhova, G. K., Lindholt, J. S., Diederichsen, A., Rasmussen, L. M., Li, D., Newton, G., Luscinskas, F. W., Liu, L., … Shi, G.-P. (2020). Eosinophils improve cardiac function after myocardial infarction. Nature Communications, 11(1), 6396. https://doi.org/10.1038/s41467-020-19297-5 Cite
Full Article