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Pulmonary Cell NewsMechanistic studies revealed roles of eosinophil IL4 and cationic protein mEar1 in blocking H2O2– and hypoxia-induced mouse and human cardiomyocyte death, TGF-β-induced cardiac fibroblast Smad2/3 activation, and TNF-α-induced neutrophil adhesion on the heart endothelial cell monolayer.
[Nature Communications]
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Liu, J., Yang, C., Liu, T., Deng, Z., Fang, W., Zhang, X., Li, J., Huang, Q., Liu, C., Wang, Y., Yang, D., Sukhova, G. K., Lindholt, J. S., Diederichsen, A., Rasmussen, L. M., Li, D., Newton, G., Luscinskas, F. W., Liu, L., … Shi, G.-P. (2020). Eosinophils improve cardiac function after myocardial infarction. Nature Communications, 11(1), 6396. https://doi.org/10.1038/s41467-020-19297-5 Cite
