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Pulmonary Cell NewsResearchers report that myeloid-specific Foxo1 knockout (Foxo1M-KO) mice were resistant to oxidative stress-induced hepatocellular damage with reduced macrophage/neutrophil infiltration, and pro-inflammatory mediators in liver ischemia/reperfusion injury.
[Cell Death & Differentiation]
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Li, C., Sheng, M., Lin, Y., Xu, D., Tian, Y., Zhan, Y., Jiang, L., Coito, A. J., Busuttil, R. W., Farmer, D. G., Kupiec-Weglinski, J. W., & Ke, B. (2020). Functional crosstalk between myeloid Foxo1–β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response. Cell Death & Differentiation, 1–15. https://doi.org/10.1038/s41418-020-00695-7 Cite
