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Pulmonary Cell NewsScientists demonstrated that melatonin had several significant effects by reducing CD11b and TLR4 expression, attenuating TLR signaling, genes involved in the inflammasome and had the potential to reduce LPS-induced inflammatory responses.
[Pediatric Research]
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Huggard, D., Kelly, L., Worrall, A., Gallagher, E., Fallah, L., Yoo, L. L., McGrane, F., Lagan, N., Roche, E., Balfe, J., Doherty, D. G., & Molloy, E. J. (2021). Melatonin as an immunomodulator in children with Down syndrome. Pediatric Research, 1–9. https://doi.org/10.1038/s41390-021-01611-6 Cite
